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. 2019 Mar 28;10:601. doi: 10.3389/fimmu.2019.00601

Figure 7.

Figure 7

Protein phosphorylation in moDC treated with native or aggregated infliximab and natalizumab. (A) Syk phosphorylation, (B) ERK 1/2 phosphorylation, and (C) Akt phosphorylation. MoDC were treated with 100 μg/mL native or aggregated antibodies. Phosphorylation was detected following 15 and 30 min of stimulation. Results are expressed as fold change over PBS control. The results from 12 independent experiments are shown. *p < 0.05; **p < 0.01; ***p < 0.001.