Table 3. Fluconazole MIC distribution for 82 isolates of C. neoformans/C. gattii species complexes tested.
| No. of isolates for which the MIC (mg l−1) wasa: | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Molecular type or specie | Number of isolates | Mean mg l−1 |
Interval mg l−1 |
MIC50 mg l−1 |
MIC90 mg l−1 |
≤0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | ≥64 |
| All isolates | 82 | 8.70 | 0.25–64 | 8 | 16 | 1 | 3 | 11 | 20 | 34 | 9 | 2 | 2 | ||
| C. neformans | 72 | 6.18 | 0.25–16 | 8 | 8 | 1 | 3 | 10 | 19 | 33 | 5 | ||||
| VNI | 51 | 7.22 | 0.25–16 | 8 | 8 | 1 | 2 | 15 | 28 | 5 | |||||
| VNII | 14 | 2.50 | 1–8 | 2 | 4 | 3 | 8 | 2 | 1 | ||||||
| VNB | 6 | 6.86 | 4–8 | 8 | 8 | 2 | 4 | ||||||||
| VNI/II | 1 | 1 | |||||||||||||
| C. gattii – VGII | 10 | 25.82 | 4–64 | 16 | 64 | 1 | 1 | 4 | 2 | 2 | |||||
Note: MIC, minimum inhibitory concentration.
aThe modal MIC for each distribution is underlined.