Table 3. Comparison of the transcription level of genes related to β-lactam antibiotics resistance in USA300 and ΔarlRS.
| ORF (USA300HOU_) |
Annotation | Ratio (Mu/WT) | |
|---|---|---|---|
| 4h | 10h | ||
| 0031 | MecA | 1.01 | 0.86 |
| 0032 | MecR1 | 0.97 | 0.79 |
| pUSA300 HOUMR0011 |
BlaZ | 0.99 | 0.93 |
| pUSA300 HOUMR0012 |
BlaR1 | 0.93 | 1.09 |
| pUSA300 HOUMR0013 |
BlaI | 0.74 | 1.05 |
| 1309 | FemA | 0.86 | 1.25 |
| 1310 | FemB | 0.84 | 1.06 |
| 1121 | penicillin-binding protein 1 | 1.04 | 1.02 |
| 1388 | penicillin binding protein 2 | 1.09 | 1.14 |
| 1554 | penicillin-binding protein 3 | 1.01 | 0.88 |
| 0662 | penicillin-binding protein 4 | 1.06 | 1.84 |
| 1001 | FmtA | 1.24 | 1.02 |
| 2150 | FmtB | 6.36 | 3.01 |
| 2151 | GlmM, phosphoglucosamine mutase | 1.11 | 0.93 |
| 1294 | FmtC | 0.95 | 1.16 |
| 0663 | AbcA | 0.95 | 0.78 |
| 0956 | TrfA, Cell Wall Antibiotic Resistance | 0.78 | 0.79 |
| 0774 | Llm, glycosyl transferase | 0.91 | 1.25 |
| 2429 | Flp protein, penicillin binding | 0.87 | 1.02 |
| 2510 | penicillinase repressor family protein | 1.68 | 1.30 |
| 1693 | metal-dependent hydrolase | 1.17 | 0.83 |
| 0955 | Spx | 0.25 | 0.16 |
| 0709 | MgrA | 0.27 | 0.20 |
| 2059 | SigB | 0.95 | 1.31 |
| 2035 | AgrA | 0.98 | 0.83 |