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. 2019 Apr 2;10:685. doi: 10.3389/fimmu.2019.00685

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Copyright © 2019 Hazeldine, Dinsdale, Harrison and Lord.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neutrophil ROS production and immature granulocyte count post-injury. Comparison of basal (A) and PMA-induced (B) ROS production by neutrophils isolated from healthy controls (HC) and trauma patients. Data are presented as area under the curve (AUC) (A) or fold increase above vehicle treated controls (B). (C,D) Frequency (C) and absolute number (D) of immature granulocytes (IG) in peripheral blood samples from healthy controls (HC) and trauma patients. Number of samples analyzed are shown below each time-point. ^*p < 0.01, ^**p < 0.001, ^***p < 0.0001 vs. HC.