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. 2019 Apr 2;10:685. doi: 10.3389/fimmu.2019.00685

Figure 3.

Figure 3

Traumatic injury results in impaired PMA-induced activation of p38 MAPK. Phosphorylation status of P38 in resting and PMA-stimulated neutrophils isolated from healthy controls (HC) and trauma patients 4–12 and 48–72 h post-injury. Data are presented as representative Western blots (B) and densitometry analysis of p38 phosphorylation in resting (A) or PMA-stimulated neutrophils at the 4–12 h (C) and 48–72 h (D) post-injury time points. HC (n = 7), 4–12 h (n = 9), and 48–72 h (n = 4). For (A) *p < 0.01, **p < 0.001 vs. HC. For (C) and (D) **p < 0.001 vs. Time 0, #p < 0.01, ###p < 0.0001 vs. HC sample at matched time point.