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. 2019 Apr 9;2019(4):CD001511. doi: 10.1002/14651858.CD001511.pub4

Richardet 1993.

Methods Randomised clinical trial with a cross‐over design
Country: France
Intention‐to‐treat analysis: not mentioned
Sample size calculation: not reported
Participants Demographic characteristics
No information
Inclusion criteria and degree of severity
Non‐infected people with histologically confirmed alcoholic hepatitis. All participants had severe hepatic failure (prothrombin time < 50%, or bilirubin > 5.6 mg/dL, or encephalopathy)
Randomisation procedure
Not mentioned
Number of participants randomised: 23
Glucocorticosteroid group: n = 12
Control group: n = 11
Interventions Prednisolone group: prednisolone 40 mg daily
Control group: placebo 40 mg daily
Duration of treatment:
Prednisolone group: 1 week of treatment followed by 1 week of no treatment
Control group: 1 week of no treatment followed by 1 week of treatment
After that, both groups received glucocorticosteroids for 3 weeks.
Duration of follow‐up: at discharge from hospital (3 months)
Outcomes Mortality
Liver biochemistry
Notes Letter sent to study authors in 2006. No answer received.
Only published as abstract
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information
Allocation concealment (selection bias) Unclear risk No information
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk No information
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No information
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No information
Selective reporting (reporting bias) Unclear risk No information
Other bias Unclear risk No information