Ding 2009.
| Study characteristics | |||
| Patient sampling | 3 local hospitals, Yantian District, Shenzhen, China; June 2007 to June 2008 Sampling: prospective consecutive sample; 2035 people with non‐traumatic, non‐comatose, non‐obstetrics presentation and 327 had acute neurologic symptoms and were included in the study. |
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| Patient characteristics and setting |
Inclusion and exclusion criteria: non‐traumatic, non‐comatose, non‐obstetrics people with acute neurologic symptoms (no further details) Participant characteristics: mean age 58 years; 48% women |
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| Index tests |
Index test: LAPSS Test administrator: emergency physicians applied LAPSS in a prehospital setting. Training: not reported |
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| Target condition and reference standard(s) |
Target condition: stroke or TIA Reference standard: final diagnosis made by a specialist group including 1 neurologist, 1 radiologist and 1 hospital doctor. |
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| Flow and timing | Unclear if diagnosis was done within 14 days of presentation. | ||
| Comparative | |||
| Diagnostic test accuracy data |
Prevalence of stroke/TIA: ischemic stroke = 44.1%, hemorrhagic stroke = 35.6%, TIA = 20.3% LAPSS: TP = 47, FP = 12, FN = 4, TN = 264 |
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| Notes |
Categorization of alternate diagnosis for participants who did not have stroke: not reported Funding: not reported |
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| Methodological quality | |||
| Item | Authors' judgement | Risk of bias | Applicability concerns |
| DOMAIN 1: Patient Selection | |||
| Was a consecutive or random sample of patients enrolled? | Yes | ||
| Was a case‐control design avoided? | Yes | ||
| Did the study avoid inappropriate exclusions? | Unclear | ||
| Prospective design | Yes | ||
| Low | Low | ||
| DOMAIN 2: Index Test Index tests | |||
| Were the index test results interpreted without knowledge of the results of the reference standard? | Yes | ||
| If a threshold was used, was it pre‐specified? | Yes | ||
| Low | Low | ||
| DOMAIN 3: Reference Standard | |||
| Is the reference standards likely to correctly classify the target condition? | Yes | ||
| Were the reference standard results interpreted without knowledge of the results of the index tests? | Unclear | ||
| Unclear | Low | ||
| DOMAIN 4: Flow and Timing | |||
| Was there an appropriate interval between index test and reference standard? | Unclear | ||
| Did all patients receive the same reference standard? | Yes | ||
| Were all patients included in the analysis? | Yes | ||
| Did all patients receive a reference standard? | Yes | ||
| Unclear | |||