Fig. 7.

Neighbor joining tree and haplotype network of the K locus suggest a single introgression event. (A) Partial neighbor-joining tree of 26 kb core nonrecombining region, based on pairwise nucleotide distances between haplotypes from 172 unrelated individuals. Haplotypes are labeled as belonging to a dog breed (“D”) or wolf population (“W”) and colored according to K^B (blue) or k^y (red). All nodes had 100% support from 5,000 bootstrap replicates. (B) Haplotype network of all K^B haplotypes sampled. Each haplotype (n = 134) consists of a 11,754 bp phased haplotype representing sites that passed filters within the 26 kb nonrecombining region around the K locus deletion. Seven unique K^B haplotypes are represented by roman numerals, with the number of haplotypes within each type indicated. Nodes are colored and shaped according to geographic origin and species (see key). Haplotype I includes wolves from Alaska (n = 8), Alberta (n = 1), Northwest Territories (n = 9), Yellowstone (n = 90), and Yukon (n = 2), and dogs (n = 1 for each of German short-haired pointer, labrador retriever, and Portuguese water dog). Haplotype IV includes Dalmatians (n = 2), German Shorthaired Pointers (n = 1), Irish Water Spaniels (n = 2), Portuguese Water Dogs (n = 1), Standard Poodles (n = 2), and Italian wolves (n = 2).