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Immunoblotting analysis of autophagy and mitophagy proteins in 12-month-old APP and non-transgenic WT mice. (A) Shows representative immunoblotting analysis of 12-month-old APP and WT mice. (B) Shows quantitative densitometry analysis of autophagy proteins. PINK1 (P = 0.02), ATG (P = 0.01), LC3BI (P = 0.01), LC3BII (P = 0.01) and TERT were significantly decreased in APP mice relative to WT mice.
