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. Author manuscript; available in PMC: 2019 Apr 9.
Published in final edited form as: ACS Biomater Sci Eng. 2018 Apr 25;4(6):2181–2192. doi: 10.1021/acsbiomaterials.8b00393

Figure 3.

Figure 3.

(A) Quantification of calcium on spiral scaffolds with various numbers of HA bilayers deposited and control adsorbed HA. A direct correlation is shown between a number of bilayers deposited and the total calcium content on scaffolds. (B) Cumulative percent calcium ion release showing the release profiles of spiral scaffolds with 0, 1, 3, and 5 bilayers of HA deposited using the layer-by-layer technique across 60 days. An initial burst release of calcium is seen in all three bilayer scaffolds, followed by a steady, sustained release from day 7–60 with a direct correlation between a number of bilayers and the cumulative amount of calcium ions released.