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. 2019 Apr 9;14(4):e0214740. doi: 10.1371/journal.pone.0214740

Fig 4. O2 flux and ROS production from permeabilised fibres with endogenous ADP.

Fig 4

Mean ± SEM measurements are shown in black for the controls (CON; n = 6), in grey for monocrotaline (MCT; n = 5) and red for metoprolol treated monocrotaline rats (MCT + BB; n = 5–6). Steady-state measurements were taken during different respiration states outlined in Fig 1. NADH-stimulated Leak (CI Leak); A: O2 flux normalised to wet weight (pmol s-1 mg-1). B: Total ROS production normalised to wet weight (pmol s-1 mg-1). Statistical significance between groups are denoted by * p < 0.05, ** p < 0.01 using one-way ANOVA with Sidak’s multiple comparisons.