Fig. 5.

Lyar mediates RPE engulfment of POSs via phagocytosis pathway. POS phagocytosis by D407 cells was performed as in Fig. 1. Phagosome marker Rab7 was detected using anti-Rab7 antibody and FITC-labeled secondary antibody, and analyzed by confocal microscopy. pHrodo signals and FITC signals are co-localized and superimposed with DAPI signals. Bar = 50 µm.