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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Pediatr Diabetes. 2019 Jan 29;20(3):263–270. doi: 10.1111/pedi.12812

Table 2:

Logistic regression significant predictors for type 1 diabetes development by age 6.

Parameter Estimate (S.E.) p-value Odds Ratio (95% CI)
Intercept −22.7 (4.3) <0.001
Age 3 IA2A status Reference = negative 2.2 (0.5) <0.001 8.7 (3.0, 25.2)
Age 3 HbA1c 3.6 (0.8) <0.001 1.4 (1.2, 1.6)*
Age 3 BMI Z Score 0.7 (0.2) 0.002 1.8 (1.2, 2.8)**
Number Autoantibodies & OGTT Fasting Insulin Level Reference = 1 autoantibody 0.001
>1 Antibody - Insulin Normal 0.6 (0.3) <0.001 11.7 (2.0, 64.3)
>1 Antibody - Insulin Low 1.5 (0.4) <0.001 28.5 (4.4, 182.9)
>1 Antibody - Insulin Missing −0.2 (0.4) 0.605 5.3 (0.8, 32.6)
RS12708716_G 0.9 (0.3) 0.008 2.4 (1.3, 4.5)***
*

Odds ratio for 0.1 unit increase in HbA1c

**

Odds ratio for 1 unit increase in Z-score

***

Odds ratio for 1 unit increase in number of alleles (0,1,2)