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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Amyotroph Lateral Scler Frontotemporal Degener. 2018 Oct 9;19(7-8):562–569. doi: 10.1080/21678421.2018.1517180

Figure 3.

Figure 3.

White matter changes in patients compared to controls.

Regions of white matter with (A) reduced fractional anisotropy (red) in pre-PLS patients (top row) and established PLS patients (bottom row) compared to healthy controls. Regions of white matter with (B) increased mean diffusivity (blue) in pre-PLS patients (top row) and established PLS patients (bottom row) compared to healthy controls. There was no significant difference between pre-PLS and PLS patients (Tract-based spatial statistics, p < 0.05, FWE corrected.)