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. 2019 Mar 15;11(3):1374–1388.

Figure 3.

Figure 3

miR-625-5p is up-regulated in IDD patients. (A) The heat maps of differentially expressed miRNAs in IDD patients. The miRNAs from a healthy control (HC), and three IDD patients with different Pfirrmann grades (IDD-1, -2 and -3) were subjected to microarray analysis. The 15 up-regulated and 15 down-regulated miRNAs with the most obvious changes are shown. (B-G) Verification of miRNA levels in samples from IDD patients. qRT-PCR was performed to verify the expression of three up-regulated miRNAs, (B) miR-625-5p, (C) miR-412 and (D) miR-10b; and three down-regulated miRNAs, (E) miR-150-5p, (F) miR-194-5p, and (G) miR-107. *P < 0.05, **P < 0.01, and ***P < 0.001.