Figure 3.

The influences of combined treatment on SKOV-3 cells. A. The growth of SKOV-3 cells treated with 40 nM BGJ398 (with or without 0.5 nM rapamycin) for 72 hours. B. The motility of SKOV-3 cells following the treatments. C-E. The expression levels of PDGF-B, VEGF-A and bFGF in SKOV-3 cells treated with 40 nM BGJ398 (with or without 0.5 nM rapamycin) for 72 hours. F. The expression of p-S6, p-Akt, p-PI3K and p-ERK1/2 following the treatments. *P<0.05 vs. the control group; #P<0.05 vs. the treatment with BGJ398 or rapamycin alone.