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. 2019 Mar 15;11(3):1498–1509.

Figure 7.

Figure 7

Recombinant fetuin B aggravated hepatic lipogenesis in HFD-fed mice. Hepatic lipid accumulation and the AMPK-/LXR-pathways were evaluated after the administration of recombinant fetuin B in mice exposed to a HFD. A: H&E staining and Oil Red O staining: HFD vs. HFD + Rec (400 ×); B: Intrahepatic TG content (P = 0.026); C: Serum TG (P = 0.011); D: Liver enzymes; E: Key protein expression of the AMPK and LXR pathways in mouse liver; F: The mRNA levels of lipid metabolic enzymes; ALT, alanine transaminase; AST, aspartate transaminase; Rec, Recombinant fetuin B. Results are the mean ± SD of three independent experiments (n = 6, each group).