Table 3.
Protein microarray data of differential cytokines in serum samples of young and aged mice
| Cytokines | Young (n=4) | Aged (n=4) | Fold-change | P-value |
|---|---|---|---|---|
| Fractalkine | 374.22±280.02 | 927.14±303.20 | 1.30891259 | 0.036789943 |
| IGFBP-5 | 3770.46±933.67 | 7525.70±1712.77 | 0.997084988 | 0.013845086 |
| IGFBP-6 | 51424.19±13712.88 | 23607.81±14511.04 | -1.123182752 | 0.031831847 |
| IL-17E | 196.77±142.51 | 524.08±43.83 | 1.413255694 | 0.015197574 |
| I-TAC | 252.24±187.10 | 911.67±419.45 | 1.853697356 | 0.043482921 |
| MDC | 54266.88±11681.25 | 92906.56±15581.87 | 0.775708524 | 0.008600027 |
| IL-15 | 882.86±226.03 | 1725.10±301.56 | 0.966422561 | 0.005095772 |
| IL-21 | 918.25±297.93 | 1432.93±133.05 | 0.642019988 | 0.032639773 |
| Leptin | 713.21±155.99 | 1491.44±347.22 | 1.06431491 | 0.013813349 |
| MIG | 818.21±173.53 | 1229.16±145.51 | 0.58711845 | 0.011561618 |
| MIP-1a | 725.58±49.16 | 1439.61±253.84 | 0.988474281 | 0.009637616 |
| GITR L | 405.28±77.57 | 965.72±340.77 | 1.252692934 | 0.042730809 |
| Lymphotactin | 293.35±105.07 | 740.02±229.24 | 1.334946457 | 0.022030626 |
| CD6 | 4055.37±955.71 | 1599.53±788.84 | -1.342186224 | 0.007969166 |
| DLL4 | 9408.85±2784.62 | 4209.44±1345.84 | -1.160388175 | 0.025022401 |
| Osteoactivin | 614.20±242.38 | 1947.85±694.65 | 1.665102441 | 0.02518712 |
| OX40 Ligand | 929.52±642.38 | 2273.15±631.55 | 1.29014186 | 0.024547193 |
| PlGF-2 | 390.71±402.33 | 1754.32±483.98 | 2.166756368 | 0.005300427 |
| ANG-3 | 1938.68±348.27 | 3833.80±1175.91 | 0.983699131 | 0.043347546 |
| CCL28 | 2287.08±569.18 | 4046.59±1117.35 | 0.823200158 | 0.042875092 |
| Epigen | 4499.02±818.32 | 7284.07±1485.46 | 0.695134832 | 0.024184841 |
| Galectin-7 | 3781.47±271.12 | 5723.31±851.63 | 0.597901321 | 0.015325596 |
| Gremlin | 996.30±172.44 | 3158.25±1096.32 | 1.664468628 | 0.027487912 |
| IFNg R1 | 5846.41±766.84 | 9667.36±2284.79 | 0.725570281 | 0.038186943 |
| MIP-1b | 1650.89±262.54 | 3722.14±748.91 | 1.172882197 | 0.007793881 |
| Persephin | 3406.18±477.69 | 6336.31±1699.62 | 0.895487101 | 0.036339497 |
| sFRP-3 | 2983.91±661.45 | 10410.41±2760.77 | 1.802749335 | 0.010307478 |
| Shh-N | 4212.82±683.68 | 6998.47±1447.66 | 0.732254669 | 0.022772598 |
| SLAM | 3678.37±529.28 | 6831.67±1439.58 | 0.893172087 | 0.016360262 |
| TECK | 740.79±118.78 | 1753.84±397.18 | 1.243386449 | 0.011079997 |
| TGFb1 | 17821.92±2221.25 | 29742.05±6181.41 | 0.738851146 | 0.024621678 |
| TWEAK | 5547.25±796.23 | 10870.80±2261.85 | 0.970614612 | 0.013238362 |
The vaules of mean flourscence indensity (MFI) are represented by mean ± SD.