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The role of UVR in the development of SLE. Abbreviation: SLE, systemic lupus erythematosus; UVR, ultraviolet radiation; IFN, interferon; IL, interleukin; TNF, tumor necrosis factor; CXCL, chemokine (C-X-C motif) ligand; CCL, chemokine (C-C motif) ligand; ICAM-1, intercellular adhesion molecule 1; HMGB1, high-mobility group protein B1; LFA-1, lymphocyte function-associated antigen; DNA methyl transferase 1, DNMT1.
