Table 2.

Inflammatory mediators in the development of SLE

Classification	Details of Inflammatory mediators
Cytokines	IFN-α, IL-1, IL-6, TNF-α, IL-12.
Chemokines	CXCL9, CXCL10, CXCL11, IL-8, CCL 5, CCL20, CCL22, chemerin.
Adhesion molecules	ICAM-1, LFA-1, e-selectin, vascular cell adhesion molecule-1.
Proteins	HMGB1.

Abbreviation: IFN, interferon; IL, interleukin; TNF, tumor necrosis factor; CXCL: chemokine (C-X-C motif) ligand; CCL, chemokine (C-C motif) ligand; ICAM-1, intercellular adhesion molecule 1; HMGB1, high-mobility group protein B1; LFA-1, lymphocyte function-associated antigen.