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. 2019 Apr 9;9:5838. doi: 10.1038/s41598-019-42084-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Venn selection of differentially regulated genes between single and double mutants. The DEGs identified in the double mutant in the current study were compared with those identified earlier in the single mutants of gpa1-5¹⁷ and gcr1-5¹⁶ and shown as up/down regulated subsets or together. (B) Hierarchical clustering of DEGs obtained from all the 3 mutants shows that gpa1-5gcr1-5 double mutant is closer to the gpa1-5 mutant than the gcr1-5 mutant.