Fig. 2.

We simplify the annotation process for each CIMT video down to six mouse clicks. As illustrated, the annotation of EUF selection is made at the video level with three mouse clicks on the three R waves of an ECG signal, while for ROI localization, the annotation is made at the frame level with one mouse click at the center of the ROI. Manually tracing the lumen-intima interface or the media-adventitia interface is tedious and laborious. To reduce workload, we eliminate the tracing by two mouse clicks on the lumen-intima and media-adventitia interfaces between two vertical dashed lines, only when requested by our proposed AFT algorithm (see the “Annotation Units” section for details)