Table 2.
Univariate analysis of baseline characteristics and clinical outcome
| Baseline characteristics | Improved/complete cure, n = 145 | No change, n = 73 | Worsening/death | p |
|---|---|---|---|---|
| Age (year), mean ± SD | 69.17 ± 13.24 | 68.05 ± 14.57 | 77.14 ± 10.79 | 0.001 |
| 80 ≤ age | 38 (26.39) | 21 (28.77) | 15 (51.72) | 0.029 |
| 70 ≤ age < 80 | 27 (18.75) | 13 (17.81) | 5 (17.24) | |
| 60 ≤ age < 70 | 46 (31.94) | 16 (21.92) | 8 (27.59) | |
| Age <60 | 33 (22.92) | 23 (31.51) | 1 (3.45) | |
| Gender, n (%) | ||||
| Male | 86 (59.31) | 40 (54.79) | 19 (65.52) | 0.595 |
| Female | 59 (40.69) | 33 (45.21) | 10 (34.48) | |
| Hypertension, n (%) | 105 (72.41) | 59 (80.82) | 22 (75.86) | 0.396 |
| Diabetes, n (%) | 41 (28.28) | 19 (26.03) | 11 (37.93) | 0.479 |
| Atrial fibrillation, n (%) | 22 (15.17) | 16 (21.92) | 3 (10.34) | 0.283 |
| Renal insufficiency, n (%) | 5 (3.45) | 2 (2.74) | 4 (13.79) | 0.072 |
| Coronary heart disease, n (%) | 13 (8.97) | 5 (6.85) | 2 (6.90) | 0.837 |
| Lung infection, n (%) | 0 (0.00) | 1 (1.37) | 0 (0.00) | 0.413 |
| Cancer, n (%) | 0 (0.00) | 1 (1.37) | 1 (3.45) | 0.083 |
| Cerebral Infraction, n (%) | 6 (4.14) | 4 (5.48) | 2 (6.90) | 0.753 |
| Other medical history, n (%) | 17 (11.72) | 10 (13.70) | 8 (27.59) | 0.081 |
| Admission CRP, median, (IQR) | 0 (0,6) | 0 (0,6) | 5 (0,20.89) | 0.005 |
| 16.5 ≤ CRP | 12 (8.45) | 6 (8.45) | 9 (31.03) | 0.030 |
| 7 ≤ CRP < 16.5 | 15 (10.56) | 8 (11.27) | 2 (6.90) | |
| 0 ≤ CRP < 7 | 115 (80.99) | 57 (80.28) | 18 (62.07) | |
| Creatinine (μmol/L), median (IQR) | 74 (62,95) | 72 (54,84) | 72.5 (58.5,89) | 0.206 |
| Uric acid (μmol/L), median (IQR) | 290 (205,371) | 309 (236,381) | 305 (54.84,369) | 0.655 |
| Blood Glucose (mmol/L), median (IQR) | 6.47 (5.64,8.63) | 6.77 (5.65,8.23) | 8.36 (6.62,10.93) | 0.008 |
| 9 ≤ glucose | 30 (21.58) | 13 (18.31) | 12 (44.44) | 0.054 |
| 7.5 ≤ glucose < 9 | 15 (10.79) | 9 (12.68) | 4 (14.81) | |
| 0 < glucose < 7.5 | 94 (67.63) | 49 (69.01) | 11 (40.74) | |
| Homocysteine (μmol/L), median (IQR) | 16.46 (11.64,21) | 14.6 (10.82,18.58) | 20 (14.43,26.98) | 0.058 |
| Systolic blood pressure (mmHg), median (IQR) | 151 (140,166) | 154.5 (143,170) | 166 (148,177.5) | 0.049 |
| 165 ≤ systolic blood pressure | 37 (25.87) | 22 (31.43) | 16 (57.14) | 0.024 |
| 155 ≤ systolic blood pressure < 165 | 25 (17.48) | 13 (18.57) | 4 (14.29) | |
| 0 < systolic blood pressure < 155 | 81 (56.64) | 35 (50.00) | 8 (28.57) | |
| Diastolic blood pressure (mmHg), median (IQR) | 85 (76,93) | 88 (77,98) | 85.5 (75.5,95.5) | 0.337 |
| Admission NIHSS, median (IQR) | 3 (2,7) | 3 (2,5) | 4 (3,9) | 0.032 |
| 20 ≤ NIHSS | 8 (5.52) | 4 (5.48) | 4 (13.79) | 0.082 |
| 4 ≤ NIHSS < 20 | 58 (40.00) | 26 (35.62) | 16 (55.17) | |
| 0 ≤ NIHSS < 4 | 79 (54.48) | 43 (58.90) | 9 (31.03) | |