Table 3.
Multivariate analysis of occurrence of worsening/death after treatment in patients with different clinical outcome
| Model | Independent variables | Levels (risk factors) | Odds ratio | 95% CI | p | |
|---|---|---|---|---|---|---|
| Lower limit | Upper limit | |||||
| Model 1 | Gender | Male versus female | 1.141 | 0.400 | 3.254 | 0.805 |
| Renal insufficiency | Absence versus presence | 0.220 | 0.035 | 1.398 | 0.109 | |
| Cancer | Absence versus presence | 0.507 | 0.013 | 19.172 | 0.714 | |
| Age | 80 ≤ age versus age <60 | 5.772 | 0.650 | 51.238 | 0.273 | |
| 70 ≤ age < 80 versus age <60 | 5.014 | 0.474 | 53.045 | 0.532 | ||
| 60 ≤ age < 70 versus age <60 | 5.662 | 0.630 | 50.909 | 0.316 | ||
| CRP | 16.5 ≤ CRP versus 0 ≤ CRP < 7 | 5.694 | 1.649 | 19.665 | 0.008 | |
| 7 ≤ CRP < 16.5 versus 0 ≤ CRP < 7 | 0.868 | 0.166 | 4.548 | 0.227 | ||
| Blood glucose | 9 ≤ blood glucose versus 0 < blood glucose < 7.5 | 2.309 | 0.780 | 6.835 | 0.521 | |
| 7.5 ≤ blood glucose < 9 versus 0 < blood glucose < 7.5 | 2.631 | 0.660 | 10.498 | 0.411 | ||
| SBP | 165 ≤ SBP versus 0 < SBP < 155 | 5.906 | 1.869 | 18.667 | 0.006 | |
| 155 ≤ SBP < 165 versus 0 < SBP <155 | 1.662 | 0.393 | 7.025 | 0.570 | ||
| NIHSS | 20 ≤ NIHSS versus 0 ≤ NIHSS < 4 | 1.867 | 0.334 | 10.445 | 0.678 | |
| 4 ≤ NIHSS < 20 versus 0 ≤ NIHSS < 4 | 1.770 | 0.601 | 5.211 | 0.644 | ||
| Model 2 | Age | Unit = 1 | 1.044 | 1.007 | 1.082 | 0.019 |
| CRP | Unit = 1 | 1.013 | 0.999 | 1.027 | 0.068 | |
| Blood glucose | Unit = 1 | 1.091 | 0.967 | 1.231 | 0.158 | |
| SBP | Unit = 1 | 1.024 | 1.004 | 1.044 | 0.016 | |
| Model 3 | Age | 80 ≤ age versus age <60 | 6.039 | 0.719 | 50.746 | 0.253 |
| 70 ≤ age < 80 versus age <60 | 6.207 | 0.637 | 60.431 | 0.326 | ||
| 60 ≤ age < 70 versus age <60 | 5.536 | 0.628 | 48.843 | 0.394 | ||
| CRP | 16.5 ≤ CRP versus 0 ≤ CRP < 7 | 6.732 | 2.108 | 21.503 | 0.002 | |
| 7 ≤ CRP < 16.5 versus 0 ≤ CRP < 7 | 0.912 | 0.179 | 4.638 | 0.200 | ||
| Blood glucose | 9 ≤ blood glucose versus 0 < blood glucose < 7.5 | 2.512 | 0.914 | 6.902 | 0.352 | |
| 7.5 ≤ blood glucose < 9 versus 0 < blood glucose < 7.5 | 2.387 | 0.620 | 9.192 | 0.531 | ||
| SBP | 165 ≤ SBP versus 0 < SBP < 155 | 5.654 | 1.888 | 16.931 | 0.006 | |
| 155 ≤ SBP < 165 versus 0 < SBP < 155 | 1.783 | 0.428 | 7.422 | 0.664 | ||
Model 1, the characteristic variables of p < 0.1 in the univariate analysis were all used as independent variables, and the logistic regression model was established by using clinical outcome of worsening/death after treatment. Model 2: Age, CRP, blood glucose, SBP were selected as independent variables. Model 3: Age, CRP, blood glucose, and SBP were selected as an independent variable.