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Glibenclamide inhibits the activation of hemin‐induced nucleotide‐binding oligomerization domain‐like receptor with a pyrin domain 3 (NLRP3) inflammasome. (a) Western blot analyses show a significant decrease in NLRP3, ASC, caspase‐1, and cl‐caspase‐1 (P20) protein expression in b.End3 cells 24 hr after the hemin treatment. (b) Bar graphs summarize the data, presented as means ± SE, from three groups (n = 3, *p < 0.05, **p < 0.01)
