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Effect of Boosting the UPRmt on Myocardial Mitochondrial Respiration in Mice Subjected to TAC or SHAM
(A to D) Oxygen consumption rate (OCR) in ventricular muscle for Complex I, Complex II, Complex I + II, and Complex IV. Mice were pre-treated with NR or vehicle and then subjected to TAC or sham. Data are mean ± SEM, n = 4 to 6/group; *p < 0.05. NR = nicotinamide riboside; TAC = transverse aortic constriction.
