Table 2.
Cross-cancer gene interactions that are present in cancer but absent in all normal networks.
| Consensus gene interactions | Number of shared cancer networks |
|---|---|
| BAD-MAP2K2 | 9 |
| CDKN1A-DDB2 | 9 |
| PIK3CA-PIK3CB | 9 |
| MAP2K1-MAPK1 | 8 |
| PIK3R1-POLK | 8 |
| ARAF-E2F3 | 7 |
| GRB2-PIK3CD | 7 |
| POLK-RB1 | 7 |
| SOS1-SOS2 | 7 |
| BAD-SOS1 | 6 |
| GSK3B-PIK3CA | 6 |
| HRAS-SOS2 | 6 |
| KRAS-MAP2K2 | 6 |
| MAPK1-NRAS | 6 |
| AKT2-BAX | 5 |
| BAD-KRAS | 5 |
| BAD-MAPK3 | 5 |
| BAK1-CDKN1A | 5 |
| E2F1-RB1 | 5 |
| E2F3-MAPK3 | 5 |
| GADD45B-MAP2K2 | 5 |
| GSK3B-PIK3CB | 5 |
| HRAS-SOS1 | 5 |
| MAPK1-MTOR | 5 |
| MAPK1-PIK3CA | 5 |
| MTOR-PIK3R3 | 5 |
| PIK3R1-SOS2 | 5 |