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. 2019 Feb 15;18(4):1787–1795. doi: 10.1021/acs.jproteome.8b00981

Figure 1.

Figure 1

Cerebellar cortex and overview of LCM-proteomics workflow. (A) Image of a cerebellar cortex tissue slice stained with H&E. Rectangle indicates area shown in (B). GM: gray matter. WM: white matter. DN: dentate nucleus. Scale bar represents 4 mm. (B) Higher magnification of area indicated in (A). Arrowheads indicate Purkinje cells. ML: molecular layer. GL: granular layer. Scale bar represents 200 μm. (C) Schematic overview of the LCM workflow. Different collection methods, lysis buffers, and digestion protocols were tested.