Table 2.

Femoral Trabecular Parameters as Evaluated by MicroCT

	Treatment Group				P Value
	3 mo		9 mo		Time	Tx	3 mo vs 9 mo		Saline vs Fluoxetine
	Saline (n = 7)	Fluoxetine (n = 7)	Saline (n = 8)	Fluoxetine (n = 7)			Saline	Fluoxetine	3 mo	9 mo
BV/TV, %	3.5 ± 0.4	2.4 ± 0.4	1.4 ± 0.3	0.9 ± 0.2	< 0.0001	0.02	< 0.0001	0.0004	0.05	0.17
Tb.N, 1/mm	2.61 ± 0.08	2.54 ± 0.14	1.72 ± 0.07	1.74 ± 0.10	< 0.0001	0.77	< 0.0001	< 0.0001	0.62	0.92
Tb.S, μm	0.38 ± 0.01	0.40 ± 0.03	0.58 ± 0.03	0.59 ± 0.04	< 0.0001	0.87	< 0.0001	< 0.0001	0.80	0.98
Tb.Th, μm	0.044 ± 0.002	0.038 ± 0.003	0.046 ± 0.002	0.047 ± 0.004	0.05	0.39	0.53	0.04	0.17	0.85
Tiss.BMD, mg Hg/cm3	905 ± 17.06	904 ± 17.28	908 ± 8.09	903 ± 15.96	0.99	0.81	0.95	0.96	0.91	0.82

Abbreviations: Tb.N, trabecular number; Tb.S, trabecular spacing; Tb.Th, trabecular thickness; Tiss.BMD, tissue bone mineral density; Tx, treatment.