Table 3.

Femoral Cortical Parameters Evaluated by MicroCT

	Treatment Group				P Value
	3 mo		9 mo		Time	Tx	3 mo vs 9 mo		Saline vs Fluoxetine
	Saline (n = 8)	Fluoxetine (n = 7)	Saline (n = 8)	Fluoxetine (n = 7)			Saline	Fluoxetine	3 mo	9 mo
Periosteal area, mm2	0.54 ± 0.06	0.41 ± 0.06	0.70 ± 0.06	0.69 ± 0.06	0.001	0.25	0.07	0.004	0.14	0.90
Periosteal circumference, mm	3.09 ± 0.03	3.01 ± 0.04	3.31 ± 0.04	3.29 ± 0.03	< 0.0001	0.19	< 0.0001	< 0.0001	0.14	0.73
C.Po, %	0.089 ± 0.001	0.090 ± 0.002	0.097 ± 0.003	0.098 ± 0.001	0.003	0.85	0.02	0.05	0.74	0.95
C.Th, mm	0.19 ± 0.003	0.19 ± 0.004	0.18 ± 0.006	0.18 ± 0.003	0.006	0.49	0.05	0.03	0.76	0.50
C.BMD, mg/cm3 HA	1273 ± 9.18	1265 ± 7.83	1255 ± 11.66	1267 ± 8.28	0.42	0.87	0.18	0.86	0.53	0.38

Abbreviations: C.Po, cortical porosity; C.Th, cortical thickness; C.BMD, cortical bone mineral density; Tx, treatment.