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. 2019 Apr 4;20(Suppl 2):186. doi: 10.1186/s12864-019-5470-2

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Accuracy measurement by normalized RMSD, PCC and SRCC vs different numbers of loci. For structures with large number of loci, the SRCC and PCC is almost one, which indicated the reconstructed structures are close to the original structures. We stopped ChromSDE, and HSA computation beyond 500 loci due to the high runtime: a Poisson distribution-based contact maps; b Binary contact maps