Table 3.
Estimated cause-specific hazard and subdistribution hazard ratios for dementia and mortality using multivariable regression models
| Covariates | Overall | Alzheimer’s disease | Vascular dementia | Unspecified dementia | ||||
|---|---|---|---|---|---|---|---|---|
| Dementia aHRa (95% CI) | Mortality aHRa (95% CI) | Dementia aHRa (95% CI) | Mortality aHRa (95% CI) | Dementia aHRa (95% CI) | Mortality aHRa (95% CI) | Dementia aHRa (95% CI) | Mortality aHRa (95% CI) | |
| Cause-specific hazard modelsa | ||||||||
| ESRD vs. non-ESRD | 2.06 (1.95–2.17) | 4.06 (3.99–4.14) | 2.71 (2.12–3.45) | 3.79 (3.73–3.86) | 2.22 (1.93–2.54) | 3.82 (3.76–3.89) | 2.01 (1.90–2.13) | 4.00 (3.93–4.08) |
| Subdistribution hazard modelsa | ||||||||
| ESRD vs. non-ESRD | 0.51 (0.49–0.54) | 3.51 (3.44–3.58) | 0.56 (0.45–0.69) | 3.76 (3.69–3.83) | 0.48 (0.42–0.53) | 3.72 (3.66–3.79) | 0.52 (0.49–0.55) | 3.53 (3.46–3.60) |
aHR adjusted hazard ratio, CI confidence interval, ESRD end-stage renal disease
aHRs were adjusted for age, sex, and selected comorbidities (diabetes mellitus, stroke, anemia, heart failure, hypertension, hyperlipidemia, coronary artery disease, peripheral vascular disease, malignancy, depression, obstructive sleep apnea, insomnia, alcoholism, traumatic brain injury, Parkinson’s disease, myocardial infarction, atrial fibrillation, hyperthyroidism, and hypothyroidism)