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. 2019 Apr 10;7:88. doi: 10.1186/s40425-019-0563-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Change in immune metagene and immunotherapy response predictive gene signatures before and after treatment in the two response groups. a. Immune gene signature expression changes in pre- and post-treatment samples from pCR cases, represented by odds-ratio and its 95% confidence interval from logistic regression. b. Immune gene signature expression changes in pre- and post-treatment samples from RD cases, represented by odds-ratio and its 95% confidence interval from logistic regression. * indicate a trend with 0.05 < p < 0.1 and ** indicate significance with p < 0.05