Table 5.

Subgroup analysis.

		Adjusted Cost Difference for Intervention vs. Control*	Adjusted QALY Difference for Intervention vs. Control*			Adjusted SBP Difference for Intervention vs. Control*
	N	Mean (95% CI)	Mean (95% CI)	ICER	95%CI**	Mean (95% CI)	ICER	95%CI**
Age
≥60 years	558	227.93 (105.87, 349.99)	0.037 (−0.01, 0.08)	6160.27	(2862.48 to 16543.90)	−5.02 (−9.48, −0.57)	45.40	(20.77 to 99.53)
<60 years	874	90.56 (10.88, 170.25)	0.042 (0.01, 0.08)	2156.19	(352.09 to 4669.80)	−5.11 ( −10.57, 0.34)	17.72	(2.98 to 35.88)
Sex
Men	660	110.55 (13.05, 208.06)	0.037 (0.01, 0.07)	2987.84	(242.03 to 7636.44)	−3.44 (−9.08, 2.18)	32.14	(1.75 to 99.95)
Women	772	164.63 (71.85, 257.40)	0.05 (0.01, 0.09)	3292.60	(1978.58 to 8162.88)	−6.41 (−11.40, −1.43)	25.68	(13.55 to 44.98)
Cardiovascular risk
High >20	857	125.40 (31.17, 219.62)	0.046 (0.01, 0.09)	2726.09	(993.01 to 6106.72)	−6.59 ( −13.36, 0.16)	19.03	(8.27 to 49.69)
Not high <20	575	152.64 (61.33, 243.94)	0.033 (0.01, 0.06)	4625.45	(1977.64 to 10674.81)	−5.42 ( −10.69, −0.15)	28.16	(15.69 to 73.69)
Body mass index
≥30 kg/m2	798	84.42 (−6.12, 174.95)	0.047 (0.01, 0.09)	1796.17	(−206.97 to 4250.66)	−4.59 (−10.38, 1.18)	18.39	(−1.79 to 50.40)
<30 kg/m2	634	210.33 (117.85, 302.80)	0.035 (0.01, 0.07)	6009.43	(3273.01 to 17477.13)	−5.65 (−10.08, −1.24)	37.23	(20.49 to 68.16)
Morisky score
Low adherence (0–5)	358	83.22 (−57.97, 224.40)	0.05 (0.001–0.10)	1664.40	(−1223.41 to 6095.28)	−4.77 (−10.03, 0.47)	17.45	(−13.09 to 54.68)
Intermediate (6–7)	406	162.13 (21.26, 303.01)	0.07 (0.015–0.12)	2316.14	(565.43 to 11989.43)	−8.60 (−13.88, −3.32)	18.85	(3.95 to 55.15)
High adherence (8)	420	147.03 (87.84, 206.21)	0.02 (−0.01–0.06)	7351.50	(1789.59 to 25628)	−3.81 ( −9.90, 2.28)	38.59	(13.55 to 120.21)