Table 3 -.

Survival analyses investigating associations of AD-PS baseline scores and their longitudinal change with date of cognitive impairment diagnosis.

	Category	Hazard ratio per unit = 0.1	95% Confidence Interval	p-values
Baseline AD-PS scores	MCI	1.29	1.10 – 1.52	0.002
	Probable dementia	1.84	1.55 – 2.18	<.0001
	MCI+probable dementia	1.51	1.35 – 1.69	<.0001
AD-PS Change (FUP-BS)	MCI	1.38	1.09 – 1.74	0.0069
	PrD	1.63	1.36 – 1.95	<.0001
	MCI+probable dementia	1.51	1.31 – 1.75	<.0001

For baseline analyses 27, 33 and 60 cases of probable dementia, MCI and MCI/probable dementia were available while 1132, 1099 and 1099 were censored respectively. For longitudinal change analyses (which spans the time from the second MRI until the end of follow-up) 54, 37 and 90 cases of probable dementia, MCI and MCI/probable dementia were available while 485, 448, and 448 were censored respectively. Analyses were adjusted by age, education and race and HT assignment.