Skip to main content
. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: J Immunol. 2019 Feb 22;202(8):2276–2286. doi: 10.4049/jimmunol.1800844

Figure 5.

Figure 5.

Shp1 deletion does not affect Slamf6 mediated upregulation of Egr2 and PLZF. (A) Frequency of live PLZF+ PSDPs from Shp1fl/fl and Shp1fl/fl CD4-cre mice after 48 hours of stimulation with the indicated immobilized antibodies. (B) PSDPs were stimulated stimulation with anti-CD3 and anti-Slamf6 antibodies for 30 min., washed and analyzed for Egr2 expression at the indicated times following stimulus withdrawal. (C) Frequency of iNKT cells in the thymus of SAP−/− Shp1fl/fl, SAP−/− Shp1fl/fl CD4-cre and SAP+/− Shp1fl/fl CD4-cre mice Representative dot plots gated on live cells are shown. Data represents individual mice and mean +/− s.e.m. of 2-3 independent experiments.