Figure 2.

Protective actions of Ac_2-26 against cardiomyocyte injury responses in vitro. Ac_2-26 (1 μM) prevents neonatal rat cardiomyocyte hypoxia-reoxygenation (H-R) injury in vitro (assessed by measuring LDH and cTnI release), whether present for the full duration of H-R (A,B, n = 7 cardiomyocyte preparation) or only post H-R (C,D, n = 5 cardiomyocyte preparation). ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 versus normoxia, ^∗P < 0.05 ^∗∗P < 0.01 versus vehicle-treated mice from the same cardiomyocyte preparation. One-way ANOVA with Dunnett’s post hoc test. n (number of different cardiomyocyte preparations) = 5. Data were presented as mean ± SEM.