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Effect of Ac2-26 on TGF-β stimulation of cardiofibroblasts in vitro. TGF-β (10 μM) downregulates (A) mFpr1 and (B) mFpf2 expression, which is elevated by Ac2-26 (10 μM) within 48 h. ####P < 0.001 versus control, ∗P < 0.05 versus TGF-β-treated cells from the same cardiofibroblast preparation. One-way ANOVA with Dunnett’s post-hoc test. n (number of different cardiofibroblasts preparations) = 7. Data were presented as mean ± SEM.
