Fig. 3. (A) Synthesis of a functionalized POx surfactant. A functional comonomer is randomly incorporated within the hydrophilic block to yield alkene (16) or alkyne (17) functionalized surfactants. (B/C) Couplings with thiol- (B) or azide-modified (C) payloads allow for modification of copolymers (NaAsc = sodium ascorbate). (D/E) 1H-NMR analysis indicates quantitative modification.
