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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: J Bone Miner Res. 2018 Apr 25;33(7):1362–1375. doi: 10.1002/jbmr.3422

Figure 5. Hdac4ob−/− mice have decreased cortical bone but not trabecular bone and PTH is unable to cause a catabolic effect in cortical bone while this is retained in trabecular bone.

Figure 5.

(A) Tibiae from female 10-week-old female Hdac4 fl/fl and Hdac4ob−/− mice treated with continuous PTH for 14 days or vehicle were used for cortical or trabecular (B) µCT analysis. (Hdac4 fl/fl; n=9, Hdac4 fl/fl with PTH; n=11, Hdac4ob−/−; n=9, Hdac4ob−/−; with PTH; n=9). Data shown are means ± SE. Different letters indicate p<0.05 vs. one another.