Skip to main content
. Author manuscript; available in PMC: 2019 Apr 10.
Published in final edited form as: FEBS J. 2018 Feb 24;285(6):1033–1050. doi: 10.1111/febs.14396

Figure 6: An increase in transcript abundance observed by RNAseq following exosome treatment correlates with mRNA payload contained within B16F0 exosomes as assayed by cDNA microarray.

Figure 6:

(A) For transcripts detected above background using cDNA microarray, an increase in transcript abundance in exosome-treated cells over untreated cells after 0.5 hours (mean ± SD, n = 3) was plotted against the average fluorescence intensity for the corresponding transcript probeset assayed by cDNA microarray (mean ± SD, n = 4). A linear relationship was quantified by a correlation coefficient of 0.902. While highlighted in panel A, RNAseq results for four of the most abundance transcripts across experimental conditions (exosome treated: circles and black solid lines, untreated: squares and red dashed lines) are shown separately for Wsb2 (B), Fam168b (C), Cmtm4 (D) and Ptpn14 (E).