KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Chemicals, Peptides, and Recombinant Proteins | ||
| TURBO DNase | Thermo Fisher Scientific | Cat no: AM2238 |
| RNasin Ribonuclease Inhibitor | Promega | Cat no: N2515 |
| Cyoloheximide | Sigma | Cat no: C1988-1G |
| Triton X -100 | Sigma | CAS No: 9002-93-1, Pack Size: X100-100ML |
| RNase I | Thermo Fisher Scientific | Cat no: AM2294 |
| SUPERaseIN | Thermo Fisher Scientific | Cat no: AM2696 |
| T4 Polynucleotide kinase | NEB | Cat no: M0201S |
| Protease Inhibitor Cocktail | Sigma | Cat no: P8340-1ML |
| Acid-Phenol:Chloroform | Thermo Fisher Scientific | Cat no: AM9722 |
| GlycoBlue Co-precipitant | Thermo Fisher Scientific | Cat no: AM9516 |
| AMPure XP beads | Beckman Coulter | Cat no: A63881 |
| Critical Commercial Assays | ||
| RNeasy Mini Kit | QIAGEN | Cat no: 74104 |
| Ribo-Zero rRNA removal kit | Illumina | Cat no: MRZH11124 |
| NEBNext® Ultra Directional RNA Library Prep Kit | NEB | Cat no: E7420S |
| SMARTer small RNA-Seq Library Preparation Kit | Clontech | Cat no. 635029 |
| TaqMan Universal Maser Mix II, with UNG | Applied Biosystems | Cat no. 4440038 |
| High-Capacity RNA-to-cDNA kit | Applied Biosystems | Cat no. 4387406 |
| Qubit RNA HS Assay Kit | Thermo Fisher Scientific | Cat no: Q32852 |
| Qubit dsDNA HS Assay Kit | Thermo Fisher Scientific | Cat no: Q32854 |
| Agilent High Sensitivity DNA Kit | Agilent | Cat no: 5067–4627 |
| Agilent RNA 6000 Pico Kit | Agilent | Cat no: 5067–1513 |
| Agilent Small RNA kit | Agilent | Cat no: 5067–1548 |
| Deposited Data | ||
| Raw and analyzed data | This Paper | GEO:GSE114064 |
| Experimental Models: Organisms/Strains | ||
| Mouse: Camk2a-cre | The Jackson Laboratory | 005359 |
| Mouse: Rpl22tm1.1Psam | The Jackson Laboratory | 011029 |
| Mouse: Fmr1−/y | The Jackson Laboratory | 00325 |
| Mouse: Rpl22tm1.1Psam,Camk2a-cre+/− | This Paper | N/A |
| Mouse:Fmr1Vy; Rpl22tm1.1Psam,Camk2a-cre+/− | This Paper | N/A |
| Oligonucleotides | ||
| Gabra2,Taqman Gene Expression Assay | Applied Biosystems | Mm00433435_m1, Cat no:4448892 |
| Arc, Taqman Gene Expression Assay | Applied Biosystems | Mm00487425_m1, Cat no:4453320 |
| Fos, Taqman Gene Expression Assay | Applied Biosystems | Mm01205647_g1, Cat no: 4453320) |
| Software and Algorithms | ||
| bowtie2 | N/A | https://github.com/BenLangmead/bowtie2 |
| STAR | N/A | https://github.com/alexdobin/STAR |
| featureCounts | N/A | http://subread.sourceforge.net/ |
| plastid | N/A | https://plastid.readthedocs.io/en/latest/installation.html |
| Samtools | N/A | http://samtools.sourceforge.net/ |
| Ribo-TISH | N/A | https://github.com/zhpn1024/ribotish |
| Ribodiff | N/A | https://github.com/ratschlab/RiboDiff |
| DeSeq2 | N/A | https://github.com/mikelove/DESeq2 |
| GSEA | Broad Institute | http://software.broadinstitute.org/gsea |