Table 3.
No. of risk factors | TP | FP | TN | FN | Se (%) | Sp (%) | PPV (%) | NPV (%) | Acc (%) |
---|---|---|---|---|---|---|---|---|---|
Derivation cohort | |||||||||
⩾1 | 244 | 256 | 7 | 0 | 100 | 3 | 49 | 100 | 50 |
⩾2 | 244 | 235 | 28 | 0 | 100 | 11 | 51 | 100 | 54 |
⩾3 | 244 | 215 | 48 | 0 | 100 | 18 | 53 | 100 | 58 |
⩾4 | 233 | 183 | 80 | 11 | 96 | 30 | 56 | 88 | 62 |
⩾5 | 219 | 120 | 143 | 25 | 90 | 54 | 65 | 85 | 71 |
⩾6 | 200 | 68 | 195 | 44 | 82 | 74 | 75 | 82 | 78 |
⩾7 | 175 | 31 | 232 | 69 | 72 | 88 | 85 | 77 | 80 |
⩾8 | 147 | 18 | 245 | 97 | 60 | 93 | 89 | 72 | 77 |
⩾9 | 110 | 11 | 252 | 134 | 45 | 96 | 91 | 65 | 71 |
⩾10 | 56 | 5 | 258 | 188 | 23 | 98 | 92 | 58 | 62 |
⩾11 | 30 | 3 | 260 | 214 | 12 | 99 | 91 | 55 | 57 |
⩾12 | 15 | 0 | 263 | 229 | 6 | 100 | 100 | 53 | 55 |
⩾13 | 6 | 0 | 263 | 238 | 3 | 100 | 100 | 52 | 53 |
Validation cohort | |||||||||
⩾1 | 147 | 183 | 5 | 0 | 100 | 3 | 45 | 100 | 45 |
⩾2 | 147 | 176 | 12 | 0 | 100 | 6 | 46 | 100 | 47 |
⩾3 | 147 | 166 | 22 | 0 | 100 | 12 | 47 | 100 | 50 |
⩾4 | 143 | 141 | 47 | 4 | 97 | 25 | 50 | 92 | 57 |
⩾5 | 136 | 96 | 92 | 11 | 93 | 49 | 59 | 89 | 68 |
⩾6 | 126 | 57 | 131 | 21 | 86 | 70 | 69 | 86 | 77 |
⩾7 | 113 | 31 | 157 | 34 | 77 | 84 | 78 | 82 | 81 |
⩾8 | 94 | 20 | 168 | 53 | 64 | 89 | 82 | 76 | 78 |
⩾9 | 67 | 13 | 175 | 80 | 46 | 93 | 84 | 69 | 72 |
⩾10 | 27 | 7 | 181 | 120 | 18 | 96 | 79 | 60 | 62 |
⩾11 | 12 | 3 | 185 | 135 | 8 | 98 | 80 | 58 | 59 |
⩾12 | 6 | 0 | 188 | 141 | 4 | 100 | 100 | 57 | 58 |
⩾13 | 2 | 0 | 188 | 145 | 2 | 100 | 100 | 56 | 57 |
TP: number of true positives; FP: number of false positives; FN: number of false negatives; TN: number of true negatives; Se: sensitivity; Sp: specificity; PPV: positive predictive value; NPV: negative predictive value; Acc: rate of accuracy of the risk score model.