Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
GPX1 could affect the PI3K-AKT pathway in NSCLC. (a) In cisplatin sensitive cell lines H460 and H1650, forced expression of GPX1 increased the level of activated AKT (detected using antibody against phosphorylated AKT) whereas downregulation of GPX1 by siRNA reduced the level of activated AKT. (b) Overexpression of GPX1 increased BCL2 level and reduced Bax expression, whereas downregulation of GPX1 inhibited BCL2 expression and increased Bax expression.
