Figure 3.

Drug Scenarios and Endpoints

Triangles indicate endpoints (relative contraindication is an intermediate endpoint). Drugs are first checked for absolute contraindications. If there are no absolute contraindications, then drugs are checked for relative contraindications and dosage. Relative contraindications affect recommendation order but do not influence start drug or increase dose recommendations. If the drug is at maximum dose, other medications are considered. If there is no active prescription or if the drug is at an intermediate dose, the system checks multiple fulfillment criteria to make a final recommendation.