Table 3. This table shows the results of a multivariable Cox proportional model including total brachial artery reactivity (TBAR) and traditional Framingham risk factors for all participants with complete data as shown in Table 2.
Variable | Hazard Ratio | Lower 95% CI | Upper 95% CI | p-value |
---|---|---|---|---|
Age (years) | 1.06 | 1.05 | 1.08 | < 0.001 |
Sex (male) | 1.64 | 1.27 | 2.11 | < 0.001 |
Current Smoker (yes) | 1.71 | 1.25 | 2.33 | 0.001 |
Diabetes (yes) | 1.70 | 1.24 | 2.32 | 0.001 |
Systolic Pressure (20.0 mmHg)† | 1.25 | 1.11 | 1.40 | < 0.001 |
LDL cholesterol (31.4 mg/dL)† | 1.05 | 0.94 | 1.19 | 0.38 |
HDL cholesterol (14.6 mg/dL)† | 0.80 | 0.70 | 0.92 | 0.002 |
Total Brachial Artery Reactivity (%)† | 0.78 | 0.67 | 0.91 | 0.001 |
Population size is 5483 (5499 discounting 16 events close to enrollment).
† Reported for a change of one standard deviation.
765 participants had low amplitude TBAR responses. These TBAR values were assigned a value of 0.0%. The statistical model is also adjusted for race/ethnicity.