Table 5. Results of multivariable Cox proportional hazards models predicting first coronary artery disease event with Total Brachial Artery Reactivity (TBAR) in a model with traditional Framingham risk factors in the participants with brachial artery diameter curves with clear minima and maxima.
| Variable | Hazard Ratio | Lower 95% CI | Upper 95% CI | p-value |
|---|---|---|---|---|
| Age (years) | 1.06 | 1.05 | 1.08 | < 0.001 |
| Sex (male) | 1.60 | 1.21 | 2.11 | 0.001 |
| Current Smoker (yes) | 1.98 | 1.42 | 2.76 | < 0.001 |
| Diabetes (yes) | 1.82 | 1.28 | 2.57 | 0.001 |
| Systolic Pressure (19.7 mmHg)† | 1.28 | 1.13 | 1.45 | < 0.001 |
| LDL-cholesterol (31.4 mg/dL)† | 1.04 | 0.91 | 1.18 | 0.58 |
| HDL-cholesterol (14.5 mg/dL)† | 0.78 | 0.67 | 0.91 | 0.002 |
| Total Brachial Artery Reactivity (9.6%)† | 0.73 | 0.61 | 0.89 | 0.001 |
Population size is 4719. Statistical model is also adjusted for race/ethnicity.
† Reported for a change of one standard deviation.