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(A) Treated samples across all doses exhibited similar uptake regardless of collagen content (high: >700 μg/mg dry weight; t-test, p = 0.26). (B) Treated samples across all doses exhibited lower uptake in the samples with high AGE concentration (high: >0.75 ng quinine fl/μg collagen; t-test, p = 0.03). Each symbol represents a biopsy half from either the L4 or L5 disc of one of four donor spines studied.
