Table 1. Description of the studies included looking for an association between toxoplasmosis and obsessive compulsive disorder.
No | First author | Publication year | Place of study | Type of study | Method | Test | Results | Age (years ± SD) | Sex (N) |
---|---|---|---|---|---|---|---|---|---|
1 | Alvarado-Esquivel C [28] | 2006 | Mexico | Case control | ELISA | IgG IgM |
Not significant | P: ≥16 C: 16–54 |
P: (-) C: (F:55, M:125) |
2 | Miman O [14] | 2010 | Turkey | Case control | ELISA IFA |
IgG IgM |
Significant | P: 18–70 C: 18–70 |
P: (F:25, M:17) C: (F:62, M:38) |
3 | Xiao Y [27] | 2010 | China | Case control | ELISA | IgG | Not significant | P: 15–65 C: 15–65 |
P: (-) C: (F:1315,M:1319) |
4 | Cong W [29] | 2015 | China | Case control | ELISA | IgG IgM |
Not significant | P: 16–91 C: 16–91 |
P: (-) C: (F:238, M:207) |
5 | Memik NÇ [16] | 2015 | Turkey | Case control | ELISA | IgG IgM |
Not significant | P: 11.84±3.19 C: 12.97±2.84 |
P: (F:23, M:19) C: (F:20, M:25) |
6 | Zaki WM [24] | 2016 | Saudi Arabia | Case control | ELISA | IgG IgM |
Not significant | P: 19–67 C: 17–64 |
P: (-) C: (F:68, M:94) |
7 | Flegr J [19] | 2016 | Czech Republic | Case control | CFT ELISA |
IgG IgM |
Not significant | P:M: 34.0±10.5 F: 36.5±12.3 C: M: 34.8±12.7 F: 32.4±11.0 |
P: (F:16, M:7) C: (F:878, M:355) |
8 | Coccaro EF [20] | 2016 | USA | Case control | ELISA | IgG | Not significant | P: 31.3±8.7 C: 33.7±8.1 |
P: (-) C: (F:46, M:64) |
9 | Flegr and Horáček a [15] | 2017 | Czech Republic | Cross sectional | CFT ELISA |
IgG IgM |
Not significant | M: 35.6±12.4 F: 32.9±12.3 |
P: (F:20, M:6) C: (F:1023, M:283) |
10 | Flegr and Horáček b [21] | 2017 | Czech Republic | Cross sectional | Not significant | M: 34.8±12.0 F: 30.5±10.9 |
P: (F:70, M:71) C: (F:2006, M:1203) |
||
11 | Afsharpaiman Sh [26] | 2017 | Iran | Case control | ELISA EIA |
IgG IgM |
P: 8.56 ± 2.5 C: 8.42 ± 1.9 |
P: (F:25, M:23) C: (F:25, M:23) |
|
12 | Akaltun I [25] | 2018 | Turkey | Case control | ELISA | IgG | Significant | P: 15.1 ± 3.9 C: 14.7 ± 2.8 |
P: (F:35, M:25) C: (F:31, M:29) |
ELISA: enzyme-linked immunosorbent assay, IFA: indirect immunofluorescence assay, CFT: complement fixation test, EIA: enzyme immunoassay, IgG: Immunoglobulin G, IgM: Immunoglobulin M, P: Pateint, C: Control, F: Female, M: Male, N: Number