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. 2019 Apr 10;13(4):e0007306. doi: 10.1371/journal.pntd.0007306

Table 1. Description of the studies included looking for an association between toxoplasmosis and obsessive compulsive disorder.

No First author Publication year Place of study Type of study Method Test Results Age (years ± SD) Sex (N)
1 Alvarado-Esquivel C [28] 2006 Mexico Case control ELISA IgG
IgM
Not significant P: ≥16
C: 16–54
P: (-)
C: (F:55, M:125)
2 Miman O [14] 2010 Turkey Case control ELISA
IFA
IgG
IgM
Significant P: 18–70
C: 18–70
P: (F:25, M:17)
C: (F:62, M:38)
3 Xiao Y [27] 2010 China Case control ELISA IgG Not significant P: 15–65
C: 15–65
P: (-)
C: (F:1315,M:1319)
4 Cong W [29] 2015 China Case control ELISA IgG
IgM
Not significant P: 16–91
C: 16–91
P: (-)
C: (F:238, M:207)
5 Memik NÇ [16] 2015 Turkey Case control ELISA IgG
IgM
Not significant P: 11.84±3.19
C: 12.97±2.84
P: (F:23, M:19)
C: (F:20, M:25)
6 Zaki WM [24] 2016 Saudi Arabia Case control ELISA IgG
IgM
Not significant P: 19–67
C: 17–64
P: (-)
C: (F:68, M:94)
7 Flegr J [19] 2016 Czech Republic Case control CFT
ELISA
IgG
IgM
Not significant P:M: 34.0±10.5
F: 36.5±12.3
C: M: 34.8±12.7
F: 32.4±11.0
P: (F:16, M:7)
C: (F:878, M:355)
8 Coccaro EF [20] 2016 USA Case control ELISA IgG Not significant P: 31.3±8.7
C: 33.7±8.1
P: (-)
C: (F:46, M:64)
9 Flegr and Horáček a [15] 2017 Czech Republic Cross sectional CFT
ELISA
IgG
IgM
Not significant M: 35.6±12.4
F: 32.9±12.3
P: (F:20, M:6)
C: (F:1023, M:283)
10 Flegr and Horáček b [21] 2017 Czech Republic Cross sectional Not significant M: 34.8±12.0
F: 30.5±10.9
P: (F:70, M:71)
C: (F:2006, M:1203)
11 Afsharpaiman Sh [26] 2017 Iran Case control ELISA
EIA
IgG
IgM
P: 8.56 ± 2.5
C: 8.42 ± 1.9
P: (F:25, M:23)
C: (F:25, M:23)
12 Akaltun I [25] 2018 Turkey Case control ELISA IgG Significant P: 15.1 ± 3.9
C: 14.7 ± 2.8
P: (F:35, M:25)
C: (F:31, M:29)

ELISA: enzyme-linked immunosorbent assay, IFA: indirect immunofluorescence assay, CFT: complement fixation test, EIA: enzyme immunoassay, IgG: Immunoglobulin G, IgM: Immunoglobulin M, P: Pateint, C: Control, F: Female, M: Male, N: Number