Comparison 24. Psychiatric comorbidities excluded ‐ Antidepressants versus benzodiazepines.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Failure to respond	1	61	Risk Ratio (M‐H, Random, 95% CI)	1.03 [0.63, 1.67]
1.1 TCAs versus BDZs	1	61	Risk Ratio (M‐H, Random, 95% CI)	1.03 [0.63, 1.67]
1.2 SSRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.3 MAOIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.4 SNRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.5 NaSSAs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.6 NDRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.7 NRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.8 Other ADs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2 Total number of dropouts	4	465	Risk Ratio (M‐H, Random, 95% CI)	1.67 [0.64, 4.36]
2.1 TCAs versus BDZs	4	465	Risk Ratio (M‐H, Random, 95% CI)	1.67 [0.64, 4.36]
2.2 SSRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.3 MAOIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.4 SNRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.5 NaSSAs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.6 NDRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.7 NRIs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.8 Other ADs versus BDZs	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]